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By L. N. Owen

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1958). ' Proc. North Annual Seminar, American College of Veterinary Pathologists. , 6 5 . S h e r m a n , M . S. (1947). 'Osteoid Osteoma. ' J. Bone Jt. Surg. 29, 918. Woods, C. G. (1961). ' J. Bone Jt. Surg. 43B, 758. 28 CHAPTER 4 O S T E O S A R C O M A I N M A N A N D DOG INCIDENCE AND SITE An osteosarcoma is a sarcoma which forms neoplastic osteoid and/or bone, the majority of the cells producing large amounts of alkaline phosphatase. In the dog it is necessary to be very critical regarding osteoid and bone in a tumour since, by comparison with m a n , there is a much greater tendency to reactive bone formation not produced by tumour cells.

J. (1966). ' J. clin. Path. 19, 65. Huff, R. W. and Brodey, R. S. (1964). ' J. Am. vet. Radiol. Soc. 5, 40. 27 BENIGN TUMOURS OF OSSEOUS ORIGIN JafFe, H . L. a n d Lichtenstein, L. (1940). ' J. Bone Jt. Surg. 22, 645. (1942). , Chicago 44, 1004. Lichtenstein, L. (1957). ' Aneurysmal Bone Cyst. ' J. Bone Jt. Surg. 39A, 873. — (1965). , p . 105. St. Louis, M o . : C. V . Mosby. — a n d Sawyer, W . R. (1964). * Benign Osteoblastoma. ' J. Bone Jt. Surg. 46A, 755. O w e n , L. N . a n d Walker, R. G.

Schwinn, C. , Soong, K. Y. and H i g i n b o t h a m , N . L . (1966). ' J. Bone Jt. Surg. 48A, 1. , C o u r t Brown, W . M . , Doll, R. a n d Sissons, H . A. (1961). l, 1782. Mays, C. W . a n d Taylor, G. N . (1964). ' Personal communication. Newton, K . A. (1967). ' Br. J. Radiol. 40, 823. Owen, L. N . (1962). ' T r e a t m e n t of 30 Cases of Spontaneous T u m o u r s in Dogs with Triethyleneglycol Diglycidyl E t h e r . ' Br. J. Cancer 16, 4 4 1 . — (1964). ' T h e T r e a t m e n t of M a l i g n a n t T u m o u r s of Bone in the D c g by Intra-arterial Injection or Perfusion of Epodyl (Triethyleneglycol Diglycidyl E t h e r ) .

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