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Cocaine poses fascinating difficulties for neurophysiologists and neuropharmacologists and there's very important new facts at the results of cocaine at the mind (its preliminary web site of motion on the mobile point now showing to be the dopamine transporter). contains chapters at the far-reaching poisonous results of cocaine, at the epidemiology and the economics of drug habit, at the earlier and current use of cocaine within the U.S. and in South the US, and at the ethical matters raised via drug use and abuse.

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Extra info for Cocaine: Scientific and Social Dimensions (Novartis Foundation Symposia)

Sample text

In our most recent work, we have investigated a suspected association between cocaine use and the occurrence of obsessivecompulsive disorder, a linkage that might well be mediated through the serotonergic activity of cocaine or its metabolites. My hope is that our discussion will centre on these studies of cocaine use and subsequent psychiatric Epidemiology of cocaine use in the USA 23 disturbances, since this work offers more challenges than basic descriptive epidemiology. The cocaine epidemic Returning to the topic of the US cocaine epidemic, I must point out that the data in Fig.

These ‘heroin-free’ daily cocaine users were drawn from a much larger pool of cocaine users found in our epidemiological samples, as we deliberately tried to restrict our attention to people who would be informative about daily cocaine use and not heroin use. Kleber: Something we began to learn in the early 1980s was that the cocaine addict was more likely to have a pattern of use consisting of ‘binges’ (1 -3 days of heavy use followed by a few days of non-use) than to be a daily user of cocaine, and that the daily user was more likely in fact to be a ‘self-medicator’.

Before turning to my second topic, I offer a summary by way of a series of unanswered questions about the dynamics of the recent cocaine epidemic: 1. The downward trend in the prevalence of cocaine use and other illicit drug use in the USA has run parallel with demographic shifts in the age structure of the population. In the US population generally, the number of younger people Epidemiology of cocaine use in the USA 25 has declined while the number of older adults has increased. This shift implies declining overall prevalence.

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